Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep967 | Thyroid (non-cancer) | ECE2015

Immunohistochemical expression of Claudin-1 in Hashimoto's thyroiditis and Graves' disease patients

Zake Tatjana , Skuja Sandra , Pekarska Katrina , Groma Valerija , Konrade Ilze , Kleina Regina

Introduction: Autoimmune thyroid diseases, including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), are complex diseases combining genetic susceptibility and environmental encounters leading to the breakdown of immune tolerance. The relationship between thyroid cancer (TC) and HT has been proven (Guarino et al. 2010), and the antibody specific association has been demonstrated (Azizi et al. 2014). Overexpression of claudin-1 appears to be an...